Andrew P. Landstrom, MD, PhD

My Locations

Duke Children's Health Center Cardiology Clinic

2301 Erwin Rd
Second floor

Durham, NC 27710-4699

Office: 919-668-4000 Get Directions

Duke Children's Hospital & Health Center

2301 Erwin Rd

Durham, NC 27710

Get Directions

About Me

Learn More About Me

I specialize in diagnosing and treating heritable arrhythmia syndromes that affect children and young adults such as long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia syndrome, and short QT syndrome. I specialize in identifying the cause of patients who have experienced a sudden cardiac arrest. I am a physician-scientist and cross-trained in pediatric cardiology, electrophysiology, human genetics, and molecular physiology. I lead an active research program that brings together clinical medicine, functional genomics, precision medicine, and molecular and cellular biology.

Current Appointments and Affiliations

Associate Professor of Pediatrics, Pediatrics, Cardiology 2024
Director of the Duke Pediatric Research Scholars Program for Physician-Scientist Development, Pediatrics 2021
Associate Professor in Cell Biology, Cell Biology 2021

Languages

English

Training

Board Certifications

American Board of Pediatrics, General Pediatrics

American Board of Pediatrics, Pediatric Cardiology

Residency

Pediatrics, Baylor College of Medicine/Texas Children's Hospital, 2012-2014

Education

MD, Mayo Clinic College of Medicine and Science (Minnesota), 2012

PhD, Mayo Graduate School (Minnesota) 2012

Fellowship

Pediatric Electrophysiology, Baylor College of Medicine/Texas Children's Hospital, 2017-2018

Pediatric Cardiology, Baylor College of Medicine/Texas Children's Hospital, 2014-2017

Clinical Focus and Research

My Research Interests

I lead a research program dedicated to identifying the causes of arrhythmias and heart muscle disease (cardiomyopathies) that can run in families. This includes diseases like long QT syndrome, short QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, sudden infant death syndrome, sudden unexplained death syndrome, hypertrophic cardiomyopathy, and arrhythmogenic right ventricular cardiomyopathy. I specialize in cardiovascular genetics and identifying at-risk family members as many of these diseases can be passed in the family.

Publications and Grants

PRIORITY: cardio-laminoPathy: fRom pathomechanIsms tO peRsonalIzed TherapY awarded by Institute of Myology 2025 - 2030
The North Carolina Congenital Heart Disease Surveillance Network awarded by Centers for Disease Control and Prevention 2024 - 2029
Determining the genetic and social determinants of heart failure and mortality in patients with congenital heart disease awarded by National Institutes of Health 2023 - 2028

Galanti, Kristian, Ghaith Sharaf Dabbagh, Fabrizio Ricci, Sabina Gallina, Roberta Giansante, Ron Jacob, Edmond Obeng-Gyimah, et al. “Dilated cardiomyopathy evaluation with Imagenomics: combining multimodal cardiovascular imaging and genetics.” ESC Heart Fail, April 24, 2025. https://doi.org/10.1002/ehf2.15307.
Hespe, Sophie, Emma S. Singer, Chloe Reuter, Brittney Murray, Elizabeth Jordan, Jessica Chowns, Stacey Peters, et al. “Clinical Validity of Autosomal Dominant ALPK3 Loss-of-Function Variants as a Cause of Hypertrophic Cardiomyopathy.” Circ Genom Precis Med, April 21, 2025, e004976. https://doi.org/10.1161/CIRCGEN.124.004976.
Perelli, Robin M., Madeleine J. Sitton, Joel D. Bohning, Adrian Pickar-Oliver, K Tyler McCullough, Mary E. Moya-Mendez, Scott Zheng, et al. “Deletion of Exon 51 in a Humanized Duchenne Muscular Dystrophy Mouse Model Abolishes Ventricular Arrhythmia Predisposition.” Circulation. Genomic and Precision Medicine, April 2025, e004867. https://doi.org/10.1161/circgen.124.004867.

Rosamilia, Michael B., Jason Williams, Courtney A. Bair, Hillary Mulder, Karen E. Chiswell, Alfred A. D’Ottavio, Robert J. Hartman, et al. “Risk Factors and Outcomes Associated with Gaps in Care in Children with Congenital Heart Disease.” In Pediatr Cardiol, 45:976–85, 2024. https://doi.org/10.1007/s00246-024-03414-y.
Verma, A., E. Da Cruz, C. Hume, A. Hunanyan, A. Landstrom, and M. Mikati. “Cardiorespiratory rate down-regulation occurs immediately before and not just during terminal seizures in the Na⁺/K⁺-ATPase sudden unexpected death in epilepsy (SUDEP) model.” In EPILEPSIA, 64:501–2, 2023.
Huggins, Erin, Maggie Holland, Laura E. Case, Janet Blount, Andrew P. Landstrom, Harrison N. Jones, and Priya S. Kishnani. “Early clinical phenotype of late-onset Pompe disease: Lessons learned from newborn screening.” In Molecular Genetics and Metabolism, 135:S57–S57. Elsevier BV, 2022. https://doi.org/10.1016/j.ymgme.2021.11.141.

Clinical Trials

Genetic Study for SCD and CHD (Heart Disease)

IRB#

PRO00094341

Ratings and Reviews

The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey. Learn more about our survey process. Responses are measured on a scale of 1 to 5 with 5 being the best score.

Overall Provider Rating

4.93 out of 5

49 ratings, 7 reviews

Patient Reviews

Patient comments are gathered from our Press Ganey Patient Survey and displayed in their entirety.
Patients are de-identified for confidentiality and patient privacy

Insurance

Duke Health contracts with most major health insurance carriers and transplant networks, including the ones listed below. Before scheduling your appointment, we strongly recommend you contact your insurance company to verify that the Duke Health location or provider you plan to visit is included in your network. Your insurance company will also be able to inform you of any co-payments, co–insurances, or deductibles that will be your responsibility. If you proceed in scheduling an appointment and your health insurance benefits do not participate with Duke, your out of pocket liability may be higher. We will contact you regarding your coverage and patient liability. If you are uninsured, learn more about our financial assistance policy.

Aetna
- Aetna Choice POS, Aetna Choice POS II
- Aetna Medicare Assure Plan (HMO D-SNP)
- Aetna/CVS Health
- Aetna Elect Choice HMO, Aetna Open Access Elect Choice
- Aetna Health Network Only, Aetna Health Network Option
- Aetna HMO
- Aetna Limited Benefit Insurance PPO
- Aetna Managed Choice POS
- Aetna Medicare Value Plan (HMO)
- Aetna Medicare Essential Plan (PPO)
- Aetna Medicare Eagle Plan (PPO)
- Aetna Open Access HMO, Open Access Aetna Select, Aetna Open Access Select, Aetna Open Access Managed Choice
- Aetna Open Choice PPO
- Aetna PCP Coordinated POS Plan
- Aetna Quality Point of Service (QPOS)
- Aetna Select HMO
- Aetna Traditional Choice
- Aetna Voluntary Indemnity Group Plan
- Aetna Whole Health – Duke WakeMed WKCC
Ambetter
- Ambetter of North Carolina
Blue Cross Blue Shield of NC
- Blue Advantage
- Blue Medicare (HMO, PPO)*
- Blue Options (123, PPO, HSA)
- Blue Select
- NC State Employees Health Plan
- *Duke HomeCare and Hospice does not participate in the plan.
CIGNA
- Cigna Behavioral Health (*Limited eligibility)
- Cigna Choice Plus
- Cigna Connect Individual Family Plan
- Cigna Open Access
- Cigna Open Access Plus
- *Please call Cigna Behavioral Heath to see if the provider is participating in your plan.
Duke Group Plans
- Duke Basic
- Duke Select
Experience Health
- Experience Health Medicare Advantage (HMO) Plan
First Health
Gateway Health Alliance
Halifax Physician-Hospital Organization
- Halifax Physician-Hospital Organization plans*
- *This plan is only accepted at Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, and Duke HomeCare & Hospice.
Healthgram

Humana
- Humana Choice (PPO)
- Humana Choice - Medicare Advantage (PPO)
- Humana ChoiceCare - Medicare Advantage (PPO)
- Humana Gold Choice - Medicare Advantage (PFFS)
- Humana Gold Plus - Medicare Advantage (HMO)
- Humana Medicare Advantage Group Plan - NC State Retirees
MedCost
Medicare
- First Medicare Direct
- Medicare Part A
- Medicare Part B
MultiPlan / Private Healthcare Systems
NC Medicaid
- WellCare of North Carolina
- UnitedHealthcare Community Plan
- NC Medicaid Direct
- Healthy Blue
- Carolina Complete Health
- AmeriHealth Caritas North Carolina
OneNet PPO
Optima Health
- FAMIS*
- Optima Family Care (Medicaid HMO in VA)*
- Optima Individual & Family (On & Off Exchange Plans)
- Optima Plus (PPO)
- Optima Vantage (HMO)
- *Duke Primary Care, Duke University Hospital, Duke Regional Hospital, and Duke Raleigh Hospital are not participating with this plan.
TRICARE
- TRICARE Prime
- TRICARE Prime Remote
- TRICARE Select
United Healthcare
- AARP Medicare Advantage Plan 2 (HMO-POS)
- AARP Medicare Complete (HMO, PPO)*
- AARP Medicare Complete Essential (HMO)*
- All Savers Alternate Funding
- All Savers Fully Insured
- United Healthcare (HMO, PPO, POS)
- United Healthcare Charter/Charter Balance/Charter Plus
- United Healthcare Choice/Choice Plus
- United Healthcare Core/Core Essential
- United Healthcare Navigate/Navigate Plus/Navigate Balanced
- United Healthcare Option PPO
- United Healthcare Passport Connect Choice/Choice Plus
- United Healthcare Passport Connect Options PPO
- United Healthcare Select/Select Plus
- United Healthcare Shared Services - Harvard Pilgrim/UHC Options PPO Network
- United Medical Resources (UMR)
- *Duke HomeCare and Hospice and mental health providers do not participate with the plan.

External Relationships

Duke requires faculty members to report certain relationships outside of their employment in order to ensure potential conflicts can be addressed. This faculty member has reported no outside activities that relate to their Duke responsibilities.