In this accredited CME activity meet a patient who presents with right lower extremity pain with exertion. What will your next steps be in the management of this patient? This activity will discuss modifiable cardiovascular risk factors, sex-specific markers of risk, and management of diabetes in the presence of cardiovascular disease. The activity starts with an introduction to a patient scenario, followed by a case-related question and brief answer explanations. Further explanation and analysis are provided to reinforce important clinical concepts.