Areas of Expertise
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Cardiac Prevention
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Heart Failure
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Heart Transplant Evaluation
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Multi-Organ Transplant
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VAD Evaluation Care
I am a cardiologist with a specialty in heart failure and transplant cardiology. I became a cardiologist because I enjoy interacting with and helping patients with complicated cardiac problems that require all of my clinical skills. It is really rewarding to see very sick challenging patients realize greater mobility and improved quality of life after working with them over months or even years. Here at Duke, we believe that developing strong personal relationships with our patients is fundamental to their success. I try to take a personal approach with each patient to encourage them to engage in a healthy lifestyle and to optimize their medical regimens to best suit their problems. A collaborative team of clinicians, nurses and staff work to achieve the best for our patients.
My research program seeks to understand how changes in calcium are decoded by a cell in order to activate signaling pathways that control gene expression, proliferation, and metabolism. In particular, we are interested in Ca2+ entry pathways including store-operated Ca2+ entry (SOCE) and transient receptor potential channels(TRPC). We have demonstrated that stromal interaction molecule 1 (STIM1) activates SOCE in muscle in order to adapt muscle function for exercise. In addition, we are interested in the role of TRPC channels in cardiac myocyte, islet, and podocyte cell proliferation. Realization of our research objectives including the discovery of therapeutic targets will have important implications for many chronic diseases, particularly heart failure.
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Patient Reviews
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